Anesthetic List for MH-Susceptible Patients

Anesthetic Agent Choice for the MH-Susceptible Patient

 

The following anesthetic agents are known triggers of MH and are not safe for use in MH-susceptible patients:

 

Unsafe Anesthetic Agents for MHS Patients

What Drugs trigger MH and are Not Safe?  

Inhaled General Anesthetics

Choroform (Trichloromethane, Methyltrichloride)

Desflurane

Enflurane

Halothane

Isoflurane

Methoxyflurane

Sevoflurane

Trichloroethylene

Xenon (Rarely Used) 

Depolarizing Muscle Relaxants Trigger MH

Succinylcholine (Suxamethonium)  

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

All other anesthetic agents outside of these two categories of Volatile anesthetic agents and depolarizing muscle relaxants are considered safe (see below for a sample).

 

Safe Anesthetic Agents for MH Patients

 

Barbiturates / Intravenous Anesthetics                 

Diazepam

Etomidate (Amidate)

Hexobarbital

Ketamine (Ketalar)

Methohexital (Brevital)

Midazolam

Narcobarbital

Propofol (Diprivan)

Thiopental (Pentothal)

 

Inhaled Non-Volatile General Anesthetic

Nitrous Oxide

 

Local Anesthetics

Amethocaine

Articaine

Bupivicaine

Dibucaine

Etidocaine

Eucaine

Lidocaine (Xylocaine)

Levobupivacaine
Mepivicaine (Carbocaine)
Procaine (Novocain)

Prilocaine (Citanest)

Ropivacaine

Stovaine

 

 

 

Narcotics (Opioids)

Alfentanil (Alfenta)

Anileridine

Codeine (Methyl Morphine)

Diamorphine

Fentanyl (Sublimaze)

Hydromorphone (Dilaudid)

Meperidine (Demerol)

Methadone

Morphine

Naloxone

Oxycodone

Phenoperidine

Remifentanil

Sufentanil (Sufenta

 

Safe Muscle Relaxants

Arduan (Pipecuronium)

Curare (The active ingredient is Tubocurraine)

Gallamine

Metocurine

Mivacron (Mivacurium)

Neuromax (Doxacurium)

Nimbex (Cisatracurium)

Norcuron (Vecuronium)

Pavulon (Pancuronium)

Tracrium (Atracurium)

Zemuron (Rocuronium)

 

Anxiety Relieving Medications

Ativan (Lorazepam)

Centrax

Dalmane (Flurazepam)

Halcion (Triazolam)

Klonopin

Librax

Librium (Chlordiazepoxide)

Midazolam (Versed)

Paxipam (Halazepam)

Restoril (Temazepam)

Serax (Oxazepam)

Tranxene (Clorazepate)

Valium (Diazepam)